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Therefore, encompassed herein is a method of treating, preventing and/or managing cancer, which comprises administering a lyophilized formulation of Compound 1 provided herein in conjunction with transplantation therapy.
The lyophilized formulation of Compound 1 provided herein can work in combination with
transplantation therapy reducing complications associated with the invasive procedure of transplantation and risk of GVHD.

In certain embodiments, a lyophilized formulation of Compound 1 provided
herein is administered to patients with various types or stages
of renal cell cancer, in combination with capecitabine, IFN, tamoxifen, IL-2, GM-CSF,
Celebrex.RTM., or a combination thereof. In some embodiments,
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a lyophilized formulation of Compound 1 provided
herein is administered to patients with multiple myeloma before,
during, or after the transplantation of autologous peripheral blood progenitor cell.
Immune cells to be used to generate modified immune cells expressing a CAR can be isolated using art-accepted, routine methods,
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